Hydroxylation and sulfation of sex steroid hormones in inflammatory liver
نویسندگان
چکیده
منابع مشابه
Hydroxylation and sulfation of sex steroid hormones in inflammatory liver
Sex steroids, also known as gonadal steroids, are oxidized with hydroxylation by cytochrome P450, glucuronidation by UDP-glucuronosyltransferase, sulfation by sulfotransferase, andO-methylation by catechol O-methyltransferase. Thus, it is important to determine the process by which inflammation influences metabolism of gonadal hormones. Therefore, we investigated the mechanism of metabolic enzy...
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Objective(s): The purpose of this study was to investigate the change in plasma anandamide (AEA) levels throughout the normal menstrual cycle, and to analyze the relationship among AEA, sex steroids and gonadotrophins. Materials and Methods: The patients were fertile women with normal menstrual cycle, proposed to get in vitro fertilization (IVF) treatment due to oviduct obstruction or male infe...
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BACKGROUND Acetaminophen (paracetamol) is one of the most common medications used for management of pain in the world. There is lack of consensus about the mechanism of action, and concern about the possibility of adverse effects on reproductive health. METHODS We first established the metabolome profile that characterizes use of acetaminophen, and we subsequently trained and tested a model t...
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ژورنال
عنوان ژورنال: The Journal of Biomedical Research
سال: 2017
ISSN: 1674-8301
DOI: 10.7555/jbr.31.20170031